About ketamine treatment

Ketamine is one of the safest and widely used medications in the world
The World Health Organisation has placed ketamine on their essential medicines list

Ketamine works by repairing brain systems damaged by chronic stress, possibly by modulation of the glutamate receptor and increasing neuroplasticity (stimulating growth of the connections between brain cells). Ketamine disrupts negative and maladaptive brain networks, allowing new positive connections to form in their place. Some have described this as similar to rebooting a computer when it is no longer functioning properly.

Ketamine, one of the most widely used medications in the world, has traditionally been used for pain control and anesthesia. Research and recent studies indicate that low dose ketamine is highly effective in treating refractory depression. Even in cases of severe depression unresponsive to other medical treatment, ketamine infusions are effective for about ⅔ of patients. Unlike many other conventional therapies, people can have profound relief from their symptoms within hours of ketamine treatment.
What is a session like?
Treatments may be tailored to the patient's specific needs and are typically described to be pleasant or euphoric.

We follow the ketamine treatment protocol that has been studied most in the treatment of depression. This is commonly referred to as the National Institute of Mental Health (NIMH) protocol. Depending on the condition, we may tailor the treatment to your specific needs. The ketamine treatment takes about an hour. When you arrive, your vital signs will be checked, and an IV will be placed. Ketamine is then administered intravenously slowly over 40 minutes. After about 20 minutes, you may notice changes in your perception, altered thought patterns and the feeling of being in a dream-like state. By the end of the 40 minutes you may feel a sense of being outside of your body. Most people describe the experience as pleasant or euphoric. You will be awake, but people often find it difficult to communicate. We recommend resting comfortably with eyeshades and calming music of your choice.
Treatments
Could ketamine help you?
Read more below to see if ketamine treatment could be beneficial for you.
Depression
TODAY, DEPRESSION IS THE LEADING CAUSE OF DISABILITY IN THE WORLD, UNDERSCORING THE GREAT NEED FOR BETTER TREATMENT OPTIONS

Approximately ⅔ OF PEOPLE HAVE A SUCCESSFUL RESPONSE TO KETAMINE INFUSIONS AND up to ⅓ OF PATIENTS EXPERIENCE REMISSION

Up to half of all people with depression are not adequately treated by initiation of conventional therapies, or cannot tolerate the side effects of antidepressant medications. Many continue to suffer from what is called treatment-resistant depression. Today, depression is the leading cause of disability in the world, underscoring the great need for better treatment options. Scientific studies done at the National Institute of Mental Health and academic centers throughout the world have found that about ⅔ of people have a successful response to ketamine infusions for treatment-resistant depression. A response is generally considered to be a 50% reduction in symptom severity as measured by depression rating scales. About ⅓ of people can have complete remission of their depression. Studies also show that ketamine significantly improves suicidal thoughts. People who do respond to treatment with ketamine have rapid relief of their suffering, and often feel significant and long-lasting improvements in mood and well-being within hours to days.

How long the treatment effects last depends on the individual. Clinical experience suggests that the effect of the recommended full course of 6 infusions usually lasts from weeks to months. It has been observed that people with a family history of alcohol abuse actually can have longer lasting effects. Benefits can be sustained by doing a single booster infusion as needed and determined by your individual response. Some people even find that they no longer need to take antidepressants. To solidify the gains you have from your treatment and to ensure long-lasting success, it is important to continue to see your primary physician or mental health care provider.
Bipolar
PEOPLE WHO DO RESPOND TO TREATMENT WITH KETAMINE HAVE RAPID RELIEF OF THEIR SUFFERING, AND OFTEN FEEL SIGNIFICANT AND LONG-LASTING IMPROVEMENTS IN MOOD AND WELL-BEING WITHIN HOURS TO DAYS

About ⅔ OF PEOPLE HAVE A SUCCESSFUL RESPONSE TO KETAMINE INFUSIONS FOR BIPOLAR DEPRESSION

Bipolar disorder can be a debilitating and difficult to treat illness. Similar success rates are observed for treating bipolar depression as those with with unipolar depression. Scientific studies done at the National Institute of Mental Health and academic centers throughout the world have found that around ⅔ of people have a successful response to ketamine infusions for bipolar depression. A response is generally considered to be a 50% reduction in symptom severity as measured by depression rating scales. About ⅓ of people have complete remission of their depression. Studies also show that ketamine significantly improves suicidal thoughts. People who do respond to treatment with ketamine have rapid relief of their suffering, and often feel significant and long-lasting improvements in mood and well-being within hours to days. Although ketamine does not cause or precipitate hypomania or mania, people in a current manic phase of bipolar disorder should not take ketamine.

How long the treatment effects last depends on the individual. Clinical experience suggests that the effect of the recommended full course of 6 infusions usually lasts from weeks to months. It has been observed that people with a family history of alcohol abuse actually have much longer lasting effects. Benefits can be sustained by doing a single booster infusion as needed and determined by your individual response. Some people even find that they no longer need to take antidepressants. To solidify the gains you have from your treatment and to ensure long-lasting success, it is important to continue to see your primary physician or mental health care provider.


Chronic pain
CHRONIC PAIN KETAMINE HAS BEEN FOUND TO BE EFFECTIVE IN MANY TYPES OF CHRONIC PAIN

PEOPLE WHO RESPOND TO TREATMENT CAN HAVE UP TO A 50% REDUCTION IN PAIN LASTING ON AVERAGE THREE MONTHS

Chronic pain can be a severe and debilitating syndrome. It is often difficult to treat, and can be associated with comorbid depression and the development of substance use disorders. Chronic pain overlaps with depression in 30-60% of people. Many treatments such as opiates and anti-inflammatory drugs also have significant side effects. Ketamine has been found to be effective in many types of chronic pain, particularly neuropathic pain.

Clinical experience with ketamine infusions for neuropathic pain suggests that people who do respond to treatment can have a 50% reduction in pain that lasts about three months on the average, followed by intermittent booster infusions as required. In some types of chronic pain, the brain cells become sensitized to pain signals causing severe discomfort even long after the physical cause of the pain is gone. Ketamine acts to stop chronic pain by blocking the NMDA receptor, cutting off the transmission of pain signals from the body to the brain. This is analogous to the negative feedback loop of a musical amplifier causing an intolerable sound, where ketamine infusions turn the amplifier off, allowing it to reset and subsequently stop interpreting the peripheral input as pain. Ketamine also significantly improves depression which sometimes accompanies chronic pain, thereby additionally improving the lives of those suffering from these disorders